March 31, 2020
Skin Allergies

Skin Allergies: This is how skin allergies spread through cosmetics, CD1A plays a special role

In the desire to look beautiful, people often spoil the colour of their real skin by using all kinds of cosmetics. People are vulnerable to many diseases such as allergies, rashes and thinning of the skin due to the toxic chemicals present in them. In order to avoid this problem, researchers have now studied and discovered a mechanism that can identify chemicals in consumer products such as lotions and perfumes that can harm our skin. Researchers say that this mechanism will allow us to adopt new ways of treating patients with skin allergies.

According to a study published in Science Immunology, the chemical factor in skin products is a major factor in skin allergies, a chemical in consumer products used to displace natural fat-like molecules in skin cells called lipids. Researchers at Columbia University in the United States said, “Allergic reactions occur in our body when T cells in the immune system know that a particular chemical is external, but T cells do not directly detect small chemicals because they are modified with larger proteins so that they are visible to T cells.

Columbia University researcher and co-author of this study Animike De Jong said,’ There are, however, many small elements present in skincare products or beauty products that cause inflammation in our skin because they are detected by T-cells. Huh, man. He said these elements should be invisible to the T-cells, but they are analogous because of which the problem deepens.

CD1A has an important role

Scientists believe that a molecule called CD1a can be responsible for making chemicals visible to T cells. CD1a is abundant on immune cells (Langerhan cells) in the outer layer of the skin. In this study, researchers have found that chemicals that detect inflammation in the skin can bind CD1a molecules to the surface of Langerhans cells and activate T cells.

Skin test is important
Researchers said that chemicals like Balsam and Farnesol, which are used extensively in cosmetics, are responsible for skin inflammation. Therefore, before using any beauty product, you must have your skin tested, so that serious skin diseases can be avoided.

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