The latest market report published by Credence Research, Inc., the global bacteriophage market was valued at US$ 567.9 million in 2017 and increased to CAGR by 3.9 per cent from 2018 to 2026.
Recently, bacteriophages or phages have been recognized as an effective tool in modern biotechnology through a multitude of research studies promoting the potential use of bacteriophages across a number of applications. Researchers have also proposed bacteriophage as a viable alternative to antibiotics for a number of antibiotic-resistant bacterial strains. They can also be used as biocontrol agents in the oil and agriculture industries.
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Bacteriophages have a unique application in the petroleum industry as bacterial fouling often results in serious damage to gas pipelines, devaluing products and therefore increasing capital costs. In addition, bacteriophages can also be used as vaccine vehicles, for the detection of the pathogenic bacterial strain, and as display systems (phage displays) for several antibodies and proteins. Bacteriophages are a diverse group of viruses that can be conveniently manipulated and therefore have significant applications in research, therapeutics and biotechnology. Phages not only control the bacterial population but also help to move genes from one bacterium to another.
Therefore, the study of bacteriophage particles offers insights into genome evolution, bacterial evolution, DNA expression and copying, and thus the development of new biotechnologies. Globally, the incessant growth in bacterial resistance to the majority of antibiotics is becoming a new driving factor for phage therapy that uses lytic phage particles as these entities are devoid of metabolic operation and do not have an affinity to eukaryotic cells. Furthermore, the utilization of bacteriophage particles in phage vaccination is also emerging as one of the promising preventive strategies currently under research. Other major areas where bacteriophages are finding renewed focus are bacterial biosensing devices, phage-display based selection of biological affinity molecules, food biopreservation, food safety, biocontrol of plant pathogens, corrosion control and biofilm control
Considering the product types, global bacteriophage market categorized into ssDNA (single-strand DNA) bacteriophage, dsDNA (double-strand DNA) bacteriophage and ssRNA (single strand RNA) bacteriophage. In 2017, dsDNA bacteriophage occupied the largest share in the global market and anticipated to continue its lead throughout the forecast period from 2018 to 2026. Majority of the cultivated viruses that have potential in culminating the widest range of bacteria are dsDNA, therefore dominating the global market. dsDNA bacteriophage also have wide applicability in phage display technologies.
In terms of geography, North America held the largest share in the global bacteriophage market due to prominent phage entities in the U.S., faster and first in the world commercialization process in the region, and significantly large patient pool suffering with bacterial infections and growing incidence of anti-biotic resistance. Moreover, established use of bacteriophages in the areas of environment and food and evolved research infrastructure with several initiatives being undertaken introducing breakthrough technologies will further drive the market during the forecast period. Asia Pacific is projected to witness the fastest progress in the global market due to rapidly evolving biotechnology infrastructure, evolving agriculture practices, and equally supportive government initiatives.
The key players currently engaged in bacteriophage market include Federal State Scientific Industrial Company MICROGEN, AmpliPhi Biosciences Corporation, EnBiotix, Phage Biotech Ltd., Fixed-Phage Limited, InnoPhage, Pherecydes Pharma, TechnoPhage SA, VersatileBio among others.
Key Market Movements:
- Growing R&D and funding for investigating bacteriophage therapy for clinical application
- Ongoing clinical trials for bacteriophage therapy for multidrug resistant bacterial infections and regulatory approvals for the same
- Increasing applications of bacteriophage in food, environment and veterinary applications
- Ongoing research for establishing bacteriophage as an effective vaccine delivery system
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